Director
B. Gino Fallone, OMRI, PhD, PPhys, FCCPM, DABMP, DABR, FAAPM, FCOMP
Professor and Director, Division of Medical Physics,
Department of Oncology, University of Alberta
Director, Dept. of Medical Physics,
Cross Cancer Institute
PhD Physics: McGill University
Fellow: Canadian College of Physicists in Medicine
Diplomat: American Board of Medical Physics
Diplomat: American Board of Radiology
Professional Physicist: Canadian Association of Physicists
Fellow: American Association of Physicists in Medicine
Fellow: Canadian Organization of Medical Physicists
Knight, Order of Merit, Italy (Cavaliere, Ordine al Merito della Repubblica Italiana)
...more
Contact
Dr. Gino Fallone
Director, Medical Physics Department
Cross Cancer Institute
11560 University Avenue
Edmonton, Alberta
Canada T6G 1Z2
Email:
or or
Research Interests
Integration of a Linac with an MRI System for Real-Time Image-Guided Radiotherpy.
Please see the Linac-MR.ca website.
Image-Guided Adaptive Radiotherapy (IGAR)
The main goal of the research program entitled "Image-guided adaptive radiotherapy (IGAR)" in CBIAR, is to achieve the maximum curing potential by precisely delivering a radiation dose distribution that is "sculpted" to the anatomical and biological extent of the tumor while delivering minimal dose to healthy tissue to reduce side effects.
The IGAR program incorporates one of the world's first human Helical TomoTherapy System, a ultra-high human whole body (3 T) MR Imaging and Spectroscopy System, an animal 9.4T MR Imaging and Spectroscopy System, an image-fusion laboratory, and the computer laboratories for the Canadian Computational Cancer Center (C4). The MR systems provide the anatomical, functional, metabolic and biochemical information to identify diseases at an earlier stage, and monitor treatment response immediately after and at intervals after treatment. The resultant information is integrated with PET images within our image fusion laboratories to design advanced adaptive radiation therapy delivered by the experimental TomoTherapy system. The C4 facilities will evaluate the clinical outcome with respect to treatment by imaging follow-up and by correlating with gene profiling information provided of PolyomX. This evaluation will allow the quantification of fundamental cancer processes and its varying treatment, in an effort to develop novel treatment strategies.
We deliver the dose by a Helical TomoTherapy system, a revolutionary treatment device that was funded by the CFI, ASRA and the ACF (Total of about $5M. Conventional modern CT and MR (1.5 T) do not show the full extent of the tumor. To obtain the full biological extent of the tumor and the healthy tissues (functional, biochemical information in addition to the anatomical information), we have received funds from the CFI and ASRIP (about $10 M) to install a ultra-high field MR system. The system comprises a 3 T MRI and MRS system ($4 M) from Philips which is far superior in imaging capabilities to conventional 1.5 T systems. In addition, we were able to acquire a 9.4 T (super high field) animal MRI and MRS system to perform studies in MR molecular imaging. The latter system brings us to the limit of what futuristic MR imaging and spectroscopy can do for cancer detection, and cancer therapy from radiation and from other cancer treatment agents. The acquisition of the latter system has been made possible with the partial financial $660K commitment from the ACF.
The IGAR facilities are unique in the world, and allow the delivery of advanced adaptive radiation treatments, offer functional and metabolic information of cancer, and quantify cancer processes, and make the Cross Cancer Institute the most advanced center in the world for cancer molecular imaging and adaptive radiation therapy.
Digital Electroradiography
The investigation of a high resolution non-contact voltage sensor to obtain latent images from xeroradiographic plates composed of amorphous Selenium (a-Se), resulting in the development of a digital radiographic system for on-line portal imaging. We are presently investigating the performance of a novel portal imaging device composed of metal/a-Se coupled to amorphous Silicon active flat-panels (thin film transistors).
Digital Portal Imaging and Automatic Image Registration and Verification
Our studies in the digital contrast enhancement of portal localization radiographs have resulted in improved visualization of the treatment area and adjacent regions, thus facilitating the task of accurate localization. Automatic registration of portal to reference images have been performed with morphological processing and correlation techniques. We have also implemented techniques to create megavoltage digital reconstructed radiographs (DRRs) of 3-D CT data to produce CT simulation of patient treatment and subsequent automatic registration to portal images. We are presently investigating the automatic registration of portal to DRRs in three dimensions for on-line verification of radiation treatment.
Inverse Treatment Planning
State-of-the art conformal therapy is a technique that achieves increased survival rate by using intensity modulated beams to deliver dose distributions that tailor a high-dose region to the tumor volume while the dose to the healthy tissue as low as possible. Optimizing techniques have developed to design the modulated beams through a process of inverse treatment planning (ITP). We have develop a novel ITP technique and now plan to incorporate clinically relevant objectives and constraints, and to incorporate emerging radiobiological information to design plans that maximizes tumor control with minimum complications.
Conformal Therapy
We are pursuing Image-Guided Adaptive Radiotherapy (IGAR) techniques that use advanced imaging modalities, conventional and ultra-high field MR, PET, CT, megavoltage CT, to deliver highly conformal therapy beams using a unique Helical TomoTherapy system within the Center for Biological Imaging and Adaptive Radiotherapy (CBIAR). Research in this avenue involves megavoltage CT, detector design and analysis, inverse planning, Monte Carlo simulation and dosimetry, radiobiological modeling, etc. Within the newly-created Canadian Computational Cancer Center, we provide through a computational and theoretical approach, the systematic simplification, quantification and visualization of cancer processes and conventional treatments into practical models that can be developed to significantly increase cure rates.
Selected Peer Reviewed Publications (since 2007)
Google Scholar link for Dr. Fallone.
List:
M H. Wang, L. J. Vos, D. Yee, Samir Patel, Nadeem Pervez, Matthew Parliament, Nawaid Usmani, Brita Danielson, John Amanie, Robert Pearcey, Sunita Ghosh, Colin Field, Gino Fallone and Albert D. Murtha;
"Clinical
Outcomes of the CHIRP trial: A Phase II Prospective Randomized Trial of Conventionally Fractionated versus Hypofractionated Radiation Therapy in Patients with High-Risk Prostate Cancer",
Pract Radiat Oncol. Sep-Oct 2021;11(5):384-393, 2021 Mar 8. pii: S1879-8500(21)00062-X. doi: 10.1016/j.prro.2021.02.011.
PubMed Link
M. Wright, B. Dietz, E. Yip, J. Yun, Z. Gabos, B.G. Fallone, K. Wachowicz;
"Time Domain Principal Component Analysis for Rapid, Real-Time MRI Reconstruction from Undersampled Data",
Med Phys. 48 (11) pp.6724-6738 (2021). Sep 15. doi: 10.1002/mp.15238.
PubMed Link
K. Purich. H. Cai, Z. Xu, A,G, Tessier, A. Black, R. Hung, E. Brown, B. Xu, P. Wu, B. Zhang, D. Xin, B.G. Fallone, R. V. Rajotte, Y. Wu, G.R. Rayat;
"MRI monitoring of transplanted neonatal porcine islets
labelled with polyvinylpyrrol coated superparamagnetic iron oxide nanoparticles in a mouse model",
Xenotransplantation 29:e12720 (16 pp) (2021. Epub 2021 Nov30.Article ID: XEN12720;
DOI: 10.1111/xen.12720
PubMed Link
Kiaran P. McGee, Neelam Tyagi, John E. Bayouth, Minsong Cao, B. Gino Fallone, Carri K. Glide-Hurst, Frank L. Goerner, Olga L. Green, Taeho Kim, Eric S. Paulson, Nathan E. Yanasak, Edward F. Jackson, James H. Goodwin,
Sonja Dieterich, David W. Jordan, Geoffrey D. Hugo, Matt A. Bernstein, James M. Balter, Kalpana M. Kanal, John D. Hazle, Norbert J. Pelc,
"Findings of the AAPM Ad Hoc committee on magnetic resonance imaging inradiation
therapy: Unmet needs, opportunities, and recommendations",
Med Phys, 48(8):4523-4531 (2021). doi: 10.1002/mp.14996
Article on the AAPM online library
R. Barta, V. Volotovsky, K. Wachowicz, B.G. Fallone, N. De Zanche,
"How thin can you go? Performance of thin copper and aluminum RF coil conductors",
Magn. Reson. Med. 2021 Apr;85(4):2327-2333. doi: 10.1002/mrm.28540. Epub 2020 Oct 15.
PubMed Link
N. Tahmasebi, P. Boulanger, J. Yun, B. G. Fallone, M. Noga, K. Punithakumar,
"Real-time Lung Tumor Tracking Using A CUDA Enabled Nonrigid Registration Algorithm for MRI,"
IEEE J Trans Eng Health Med, 8 4300308 (9 pp) (2020). doi: 10.1109/JTEHM.2020.2989124.
PubMed Link.
B. Dietz, J. Yun, E.Yip, Z.Gabos, B.G. Fallone, K. Wachowicz,
"Single Patient Convolutional Neural Networks for Real-time MR Reconstruction: Coherent Low-Resolution versus Incoherent Undersampling,"
Phys Med Biol. 65(8):08NT03 (13 pp) (2020). doi: 10.1088/1361-6560/ab7d13.
PubMed Link
R. Barta, A. Ghila, V. Volotovsky, K. wachowicz, S. Rathee, B.G. Fallone, N. de Zanche,
"Impact of a Parallel Magnetic Field on Radiation Dose Beneath Thin Copper and Aluminum Foils,"
Biomed. Phys. & Eng. Express, 6 137002 (7 pp) (2020). doi: 10.1088/2057-1976/ab7cf2.
IOPscience Link.
R. Yang, D.M. Santos, B.G. Fallone, and J. St-Aubin,
"Feasibility of energy adaptive angular meshing for perpendicular and parallel magnetic fields in a grid based Boltzmann solver,"
Biomed. Phys. Eng. Express 6 025006 (11pp) (2020). doi: 10.1088/2057-1976/ab6e15
IOPscience Link.
B. Dietz, J. Yun, Z. Gabos, B.G. Fallone, K. Wachowicz,
"Single Patient Convolutional Neural Networks for Real-time MR Reconstruction: A Proof of Concept Application in Lung Tumor Segmentation for Adaptive
Radiotherapy,"
Phys Med Biol. 64(19):195002 (15 pp) (2019), Epub 2019 Sep 23. doi: 10.1088/1361-6560/ab408e
PubMed Link.
B.J. Dobberthien, A. Tessier, M. Sawyer, B.G. Fallone, A. Yahya,
"PRESS timings for resolving 13C4-glutamate 13C signal at 9.6 T,"
NMR Biomed. 32(12):e4180 (13pp) (2019). Epub 2019 Sep 13. doi: 10.1002/nbm.4180.
PubMed Link.
R. Yang, D.M. Santos, B.G. Fallone, J. St-Aubin,
"A novel transport sweep architecture for efficient deterministic patient dose calculations in MRI-guided radiotherapy,"
Phys Med Biol. 2019 Sep 19;64(18):185012. doi: 10.1088/1361-6560/ab35bc.
PubMed Link.
M. Reynolds, S. Rathee and B.G. Fallone,
"Technical Note: Sensitive volume effects on ion chamber responses in longitudinal magnetic fields,"
Med Phys, 46(7):3306-3310 (2019). doi: 10.1002/mp.13565. Epub 2019 May 21.
PubMed Link.
D. M. Santos, K.Wachowicz, B. Burke, and B. Gino Fallone,
"Proton beam behaviour in the presence of an MRI unit: effects of both the primary Bo and time-varying gradient magnetic fields,"
Medical Physics, 46(2):822-838 (2019). Epub 2018 Dec 18. doi: 10.1002/mp.13309.
PubMed Link.
S. Rathee, B.G. Fallone, S. Steciw,
"Technical Note: EPID's response to 6 MV photons in a strong, parallel magnetic field,"
Medical Physics, 46(1):340-344 (2019). DOI 10.1002/mp.13285; Epub 2018 Dec 13,
PubMed Link.
B. Dietz, K. Wachowicz, B.G. Fallone,
"Nomenclature for real-time magnetic resonance imaging,"
Magn Reson Med, 81(3):1483-1484 (2019). Epub 2018 Nov 19. doi: 10.1002/mrm.27487.
Wiley Online Link;
PubMed Link.
B. Dietz, J. Yun, Z. Gabos, B.G. Fallone, K. Wachowicz,
"Single Patient Convolutional Neural Networks for Real-time MR Reconstruction: A Proof of Concept Application in Lung Tumor Segmentation for Adaptive
Radiotherapy,"
Phys Med Biol. 64(19):195002 (2019). doi: 10.1088/1361-6560/ab408e.
PubMed Link.
A. Ghila, B.G. Fallone, S.Rathee,
"Experimental verification of EGSnrc calculated depth doses within a parallel magnetic field in a lung phantom,"
Medical Physics 45(12):5653-5658 (2018). Epub 2018 Oct 23. doi: 10.1002/mp.13215.
PubMed Link;
Wiley Online Link.
S. Rathee, B.G. Fallone, S. Steciw,
"Technical Note: EPID's response to 6 MV photons in a strong, parallel magnetic field,"
Medical Physics, 46(1):340-344. Epub 2018 Dec 13. doi: 10.1002/mp.13285.
PubMed Link.
N. Tahmasebi, P. Boulanger, J. Yun, B.G. Fallone, K. Punithakumar,
"Tracking Tumor Boundary Using Point Correspondence for Adaptive Radio Therapy",
Comput Methods Program Biomedicine, 2018 Oct;165:187-195. Epub 2018 Aug 22. doi: 10.1016/j.cmpb.2018.08.002.
PubMed Link.
K. Wachowicz, B. Murray, B.G. Fallone,
"On the direct acquisition of beam’s-eye-view images in MRI for integration with external beam radiotherapy,"
Physics Medicine Biology, 63 (12), 125002 (11pp), (2018). doi: 10.1088/1361-6560/aac5b9
PubMed Link
Physics World Article.
A. Abulrob, S. Corluka, B. Blasiak, B.G. Fallone, D. Ponjevic, J. Matyas, B.Tomanek,
"LyP-1 Conjugated Nanoparticles for MRI imaging of triple negative breast cancer,"
Molecular Imaging and Biology, 20, 428-435 (2018). Online Nov 3, 2017. doi: 10.1007/s11307-018-1189-8
PubMed Link.
R. Yang, O. Zelyak, B.G. Fallone, J. St.Aubin,
"A novel upwind stabilized discontinuous finite element angular framework for deterministic dose calculations in magnetic fields,"
Physics Medicine Biology. 2018 Jan 30;63(3):035018. doi: 10.1088/1361-6560/aaa2b1.
PubMed Link.
E. Yip, J. Yun, Z. Gabos, S. Baker, D. Yee, K. Wachowicz, S. Rathee, and B. G. Fallone,
"Evaluating performance of a user trained MR lung tumor autocontouring algorithm in the context of intra- and interobserver
variations,"
Med Phys. 2018 Jan;45(1):307-313. Epub 2017 Dec 15. doi: 10.1002/mp.12687.
PubMed Link.
O. Zelyak, B. G. Fallone, J. St. Aubin,
"Stability Analysis of a Deterministic Dose Calculation for MRI-Guided Radiotherapy,"
Phys Med Biol. 2017 Dec 14;63(1):015011. doi: 10.1088/1361-6560/aa959a.
PubMed Link.
A. Ghila, S. Steciw, B.G. Fallone, S.Rathee,
"Experimental verification of EGSnrc Monte Carlo calculated depth doses within a realistic parallel magnetic field in a polystyrene phantom,"
Medical Physics 2017 Sep;44(9):4804-4815. Epub 2017 Jul 17. doi: 10.1002/mp.12413.
PubMed Link.
B. Dietz, E. Yip, J. Yun, B.G. Fallone, K. Wachowicz,
"Real-time dynamic MR image reconstruction using compressed sensing and principal component analysis (CS-PCA): Demonstration in lung tumor,"
Medical Physics, 2017 Aug;44(8):3978-3989. Epub 2017 Jun 28. doi: 10.1002/mp.12354.,
PubMed Link.
M. Reynolds, S. Rathee, B.G Fallone,
"Technical Note: Ion Chamber Angular Dependence in a Magnetic Field,"
Medical Physics 2017 Aug;44(8):4322-4328. Epub 2017 Jul 10. doi: 10.1002/mp.12405.,
PubMed Link.
N. Pervez, C. Drodge, D. Yee, M. Parliament, B.G. Fallone, R. Pearcey,
"Late toxicity and outcomes in high-risk prostate cancer patients treated with Hypofractionated IMRT and Long-term Androgen Suppression
Treatment,"
Am J Clinical Oncology 2017 Apr;40(2):200-206. doi: 10.1097/COC.0000000000000133.,
PubMed Link.
S Y Tari, K. Wachowicz, B.G. Fallone,
"A Non-Axial Superconducting Magnet Design for Optimized Patient Access and Minimal SAD for Use in a Linac-MR Hybrid: Proof of Concept,"
Phys Med Biol. 2017 Apr 21;62(8):N147-N160. Epub 2017 Feb 8. doi: 10.1088/1361-6560/aa5f20.,
PubMed Link.
D. Baillie, B.G. Fallone, S. Steciw,
"Design and simulation of a short, variable-energy 4 to 10 MV linear accelerator waveguide,"
Medical Physics, 2017 Jun;44(6):2124-2131. Epub 2017 May 12. doi: 10.1002/mp.12260,
PubMed Link.
E. Yip, J. Yun, K. Wachowicz, Z. Gabos, B.G. Fallone,
"Sliding Window Prior Data Assisted Compressed Sensing for MRI tracking of lung tumours,"
Med Phys. 2017 Jan;44(1):84-98. doi: 10.1002/mp.12027.,
PubMed Link.
J.Yun, E. Yip, Z. Gabos, K. Wachowicz, S. Rathee, B.G. Fallone,
"Improved lung tumor autocontouring algorithm for intrafractional tumor tracking using 0.5 T linac-MR,"
Biomedical Physics and Engineering Express, 2 067004 (5 pp) (2016). doi: 10.1088/2057-1976/2/6/067004
A. Ghila, B.G. Fallone, S. Rathee,
"Influence of Standard RF Coil Materials on Surface and Buildup Dose from a 6MV Photon Beam in Magnetic Field,"
Med Phys. 2016 Nov;43(11):5808. doi: 10.1118/1.4963803.,
PubMed Link.
A. Heikal, K. Wachowicz, B.G. Fallone,
"Correlation between k-space sampling pattern and MTF in compressed sensing MRSI,"
Med Phys. 2016 Oct;43(10):5626. doi: 10.1118/1.4962930.,
PubMed Link.
Larissa J. Vos, Michele Janoski, Keith Wachowicz, Atiyah Yahya, Oleksandr Boychak, John Amanie, Nadeem Pervez, Matthew B. Parliament, Edith Pituskin,
B. Gino Fallone, Nawaid Usmani,
"Role of Serial Multiparametric Magnetic Resonance Imaging in Prostate Cancer Active Surveillance,"
World J. Radiology, 2016 Apr 28;8(4):410-8. doi: 10.4329/wjr.v8.i4.410.,
PubMed Link.
K Wachowicz, N. DeZanche, V. Volotovsky, B.G. Fallone,
"CNR considerations for rapid real-time MRI tumor tracking in radiotherapy hybrid devices: Effects of Bo field strength,"
Med Phys. 2016 Aug;43(8):4903. doi: 10.1118/1.4959542.,
PubMed Link.
J. St. Aubin, A. Keyvanloo, B.G. Fallone,
"Discontinuous finite element space-angle treatment of the first order linear Boltzmann transport equation with magnetic fields: application to MRI-guided radiotherapy,"
Med Phys. 2016 Jan;43(1):195. doi: 10.1118/1.4937933. ,
PubMed Link.
A Keyvanloo, B Burke, J St. Aubin, D Baillie, K Wachowicz, B Warkentin, S Steciw, and
B G Fallone,
"Minimal skin dose increase in longitudinal rotating biplanar Linac-MR systems: examination of radiation energy and flattening filter design,"
Phys Med Biol. 2016 May 7;61(9):3527-39. Epub 2016 Apr 6. doi: 10.1088/0031-9155/61/9/3527.,
PubMed Link.
B.J. Dobberthien, A. G. Tessier, B.G. Fallone, A. Yahya,
"Glycine Measurement in Rat Brain at 9.4 T using an Optimized PRESS Sequence,"
Biomedical Physics & Engineering Express, 2, 027003 (8 pp), (2016).
D. Breitkreutz, B.G. Fallone, A. Yahya,
"Effect of J-Coupling on 1.3 ppm Lipid Methylene Signal Acquired with Localized Proton Magnetic Resonance Spectroscopy at 3 T,"
NMR Biomed. 2015 Oct;28(10):1324-31. Epub 2015 Aug 28. doi: 10.1002/nbm.3387.,
PubMed Link.
M. Reynolds, B.G. Fallone, S. Rathee,
"Response Measurement for Select Radiation Detectors in Magnetic Fields,"
Med Phys. 2015 Jun;42(6):2837-40. doi: 10.1118/1.4919681. ,
PubMed Link.
J.Yun, E. Yip, Z. Gabos, K. Wachowicz, S. Rathee, B.G. Fallone,
"Neural-network based autocontouring algorithm for intrafractional lung-tumor tracking using linac-MR,"
Med Phys. 2015 May;42(5):2296-310. doi: 10.1118/1.4916657.,
PubMed Link.
D. Baillie, J. St.Aubin, B.G. Fallone, S. Steciw,
"FEM design and simulation of a short, high-energy, S-band linac with Monte Carlo dose simulations,"
Med Phys. 2015 Apr;42(4):2044-53. doi: 10.1118/1.4915953.,
PubMed Link.
A. Bingolbali, B.G. Fallone, A. Yahya,
"Comparison of Optimized Long Echo Time STEAM and PRESS Proton MR Spectroscopy of Lipid Olefinic Protons at 3 Tesla,"
J Magn Reson Imaging. 2015 Feb;41(2):481-6. Epub 2013 Dec 12. doi: 10.1002/jmri.24532.,
PubMed Link.
J. St.Aubin, A. Keyvanloo, C. Vassiliev, B.G. Fallone,
"Inclusion of magnetic field effects in a deterministic solution to the first order linear Boltzmann transport equation",
Med Phys. 2015 Feb;42(2):780-93. doi: 10.1118/1.4905041.,
PubMed Link.
A.M. Maunder, M. Daneshmand, B.G. Fallone, N. de Zanche,
"Experimental Verification of SNR and Parallel Imaging Improvements Using Composite Coil Arrays,"
NMR Biomed. 2015 Feb;28(2):141-53. Epub 2014 Nov 11. dio: 10.1002/nbm.3230.
PubMed Link.
Arash Panahifar, Jacob L. Jaremko, Anthony G. Tessier, Robert G. Lambert, Walter P. Maksymowych,
B. Gino Fallone, Michael R. Doschak,
"Development and reliability of a multi-modality scoring system for evaluation of disease progression in pre-clinical models of osteoarthritis: Celecoxib may possess
disease-modifying properties,"
Osteoarthritis Cartilage. 2014 Oct;22(10):1639-50. doi: 10.1016/j.joca.2014.06.013.,
PubMed Link.
M. Reynolds, B.G. Fallone, S. Rathee,
"Dose response of selected solid state detectors in applied homogeneous transverse and longitudinal magnetic fields",
Med Phys. 2014 Sep;41(9):092103. doi: 10.1118/1.4893276.,
PubMed Link.
A.G. Tessier,A. Yahya, M. Larocque, B.G. Fallone, A. Syme,
"Longitudinal Evaluation of the Metabolic Response of a Tumor Xenograft Model to Single Fraction Radiation Therapy Using Magnetic Resonance Spectroscopy,"
Phys Med Biol. 2014 Sep 7;59(17):5061-72. Epub 2014 Aug 13. doi: 10.1088/0031-9155/59/17/5061.,
PubMed Link.
E. Yip, J. Yun, K. Wachowicz, Z. Gabos, A. Heikal, S. Rathee, B.G. Fallone
"Prior Data Assisted Compressed Sensing: A Novel MR imaging strategy for real time tracking of lung tumors",
Featured in medicalphysicsweb.org,
Med Phys. 2014 Aug;41(8):082301. doi: 10.1118/1.4885960.,
PubMed Link.
D.L. Anderson, R. Mirzayans, B. Andrais, L.A. Siegbahn, B.G. Fallone, B. Warkentin,
"Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated x-ray
microbeams: Lack of correlation between persistent γH2AX foci and apoptosis,"
J Synchrotron Radiat. 2014 Jul;21(Pt 4):801-10. Epub 2014 Jun 13. doi: 10.1107/S1600577514011424.,
PubMed Link.
B. G. Fallone,
"The Rotating Biplanar-Magnetic Resonance Imaging System,"
Semin Radiat Oncol. 2014 Jul;24(3):200-2. doi: 10.1016/j.semradonc.2014.02.011. , Invited talk,
Featured in medicalphysicsweb.org,
PubMed Link.
M.R. Paudel, M. Mackenzie, B.G. Fallone, S. Rathee,
"Clinical evaluation of normalized metal artifact reduction in kVCT using MVCT prior images (MVCT-NMAR) for radiotherapy treatment planning,"
Int J Radiat Oncol Biol Phys. 2014 Jul 1;89(3):682-9. Epub 2014 Apr 18. doi: 10.1016/j.ijrobp.2014.02.040.,
PubMed Link.
R.L. Lagore, B.R. Roberts, C. Possanzini, C. Saylor, B.G. Fallone, N. DeZanche,
"A system for automated noise parameter measurements on MR preamplifiers and application to high B fields,"
NMR Biomed. 2014 Aug;27(8):926-38. Epub 2014 May 29. doi: 10.1002/nbm.3138.,
PubMed Link.
A.M. Maunder, M. Daneshmand, P. Mousavi, B. G. Fallone, N. De Zanche,
"Stray capacitance between magnetic resonance imaging coil elements: Models and application to array decoupling,"
IEEE Trans Trans Microwave Theory and Techniques, 61(12) , pp.4664-4677 (2013). doi: 10.1109/TMTT.2013.2288236.
D. Anderson, B. Andrais, R. Mirzayans, E.A. Siegbahn , B.G. Fallone and B. Warkentin,
"Comparison of two methods for measuring γ-H2AX nuclear fluorescence as a marker of DNA damage in cultured human cells:
applications for microbeam radiation therapy,"
Journal of Instrumentation, 8(6):C06008 - June 2013. doi: 10.1088/1748-0221/8/06/C06008.
M. Paudel, M. Mackenzie, B.G. Fallone, S. Rathee,
"Evaluation of normalized metal artifact reduction (NMAR) in kVCT using MVCT prior images for radiotherapy treatment planning,"
Med Phys. 2013 Aug;40(8):081701. doi: 10.1118/1.4812416.
PubMed Link.
A. Heikal, K. Wachowicz, B.G. Fallone,
"MTF behaviour of compressed sensing MR spectroscopic imaging,"
Med Phys. 2013 May;40(5):052302. doi: 10.1118/1.4800642.
PubMed Link
J. Yun, K.Wachowicz, M. Mackenzie, S. Rathee, D. Robinson, B.G. Fallone,
"First Demonstration of Intrafractional Tumor-Tracked Irradiation Using 2D Phantom MR Images on a Prototype linac-MR,"
Med Phys. 2013 May;40(5):051718. doi: 10.1118/1.4802735.
PubMed Link
M. Reynolds, B.G. Fallone, S. Rathee,
"Dose Response of Selected Ion Chambers in Applied Homogeneous Transverse and Longitudinal Magnetic Fields,"
Med Phys. 2013 Apr;40(4):042102. doi: 10.1118/1.4794496.
PubMed Link
D. Baillie, J St.Aubin, B.G. Fallone, S. Steciw,
"Feasibility of producing a short, high energy S-band linear accelerator using a klystron power source,"
Med Phys. 2013 Apr;40(4):041713. doi: 10.1118/1.4794928.
PubMed Link
A. Troitskaia, B.G. Fallone, A. Yahya,
"Long Echo Time Proton Magnetic Resonance Spectroscopy for Estimating Relative Measures of Lipid Unsaturation at 3 T,"
J Magn Reson Imaging. 2013 Apr;37(4):944-9. Epub 2012 Oct 19. doi: 10.1002/jmri.23868.
PubMed Link
A. Keyvanloo, B. Burke, B. Warkentin, T. Tadic, S. Rathee, C. Kirkby, D.M. Santos, B.G. Fallone,
"Skin Dose in Longitudinal and Transverse Linac-MRIs using Monte-Carlo and realistic 3D MRI field models,"
Med Phys. 2012 Oct;39(10):6509-21. doi: 10.1118/1.4754657.
PubMed Link
M.R. Paudel, M.Mackenzie, B.G. Fallone, S. Rathee,
"Evaluation of metal artifacts in MVCT systems using a model based correction method,"
Med Phys. 2012 Oct;39(10):6297-308. doi: 10.1118/1.4754647.
PubMed Link
B.Burke, K. Wachowicz, B.G. Fallone, S. Rathee,
"Effect of radiation induced current on the quality of MR images taken with an integrated linac-MR system,"
Med Phys. 2012 Oct;39(10):6139-47. doi: 10.1118/1.4752422.
PubMed Link
B. Burke, A. Ghila, B.G. Fallone, S. Rathee,
"Radiation induced current in the RF coils of integrated Linac-MR systems: the effect of buildup and magnetic field,"
Med Phys. 2012 Aug;39(8):5004-14. doi: 10.1118/1.4737097.
PubMed Link
J.Yun, M. Mackenzie, S. Rathee, D. Robinson, B.G. Fallone,
"An artificial neural network (ANN) based lung tumor motion predictor for intrafractional MR tumor tracking,"
Med Phys. 2012 Jul;39(7):4423-33. doi: 10.1118/1.4730294.
PubMed Link
D. Robinson, D. Liu, S. Steciw, C. Field, H. Daly, S. Kumar, G. Fallone, M. Parliament, J. Amanie,
"An evaluation of the Clarity 3D ultrasound system for prostate localization,"
J Appl Clin Med Phys. 2012 Jul; 13(4): 100–112. Epub 2012 Jul 5. doi: 10.1120/jacmp.v13i4.3753.
PubMed Link
K. Wachowicz, T. Tadic, B.G. Fallone,
"Geometric distortion and shimming considerations in a rotating MR-linac design due to the influence of low-level external magnetic fields,"
Med Phys. 2012 May;39(5):2659-68. doi: 10.1118/1.3702591.
PubMed Link
D. Anderson, E.A. Siegbahn, B.G. Fallone, R. Serduc, B. Warkentin,
"Evaluation of dose-volume metrics for microbeam radiation therapy dose distributions in head phantoms of various sizes using Monte Carlo
simulations,"
Phys Med Biol. 2012 May 21;57(10):3223-48. Epub 2012 May 1. doi: 10.1088/0031-9155/57/10/3223.
PubMed Link
J. Yun, E. Yip, K. Wachowicz, S. Rathee, M. Mackenzie, D. Robinson, B.G. Fallone,
"Evaluation of a lung tumor autocontouring algorithm for intra-fractional tumor tracking using low-field MRI A phantom study,"
Med Phys. 2012 Mar;39(3):1481-94. doi: 10.1118/1.3685578.
PubMed Link
D.M. Santos, J. St-Aubin, B.G. Fallone, S. Steciw,
"Magnetic shielding investigation for a 6 MV in-line linac within the parallel configuration of a linac-MR system,"
Med Phys. 2012 Feb;39(2):788-97. doi: 10.1118/1.3676692.Front page of Issue
Selected for Virtual Journal of Biological Physics Research, Feb 1, 2012.
PubMed Link
T. Tadic and B.G. Fallone,
"Design and optimization of superconducting MRI magnet systems with magnetic materials,"
IEEE Trans Applied Superconductivity, 22(2), pp.4400107-4400107 (2012). doi: 10.1109/TASC.2012.2183871.
A. Yahya, A. Tessier, B.G. Fallone,
"Effect of j-coupling on lipid composition determination with localized proton magnetic resonance spectroscopy at 9.4 T,"
J Magn Reson Imaging. 2011 Dec;34(6):1388-96. Epub 2011 Sep 23. doi: 10.1002/jmri.22792.
PubMed Link
D. Bartusik, B. Tomanek, B. Blicharska, G. Fallone,
"Magnetic resonance assays of haloperidol in human serum albumin,"
Medicinal Chemistry Research, 20, pp. 62-66(2011).
J-D Jutras, B.G. Fallone, N.deZanche,
"Efficient multichannel coil data compression: A prospective study for distributed detection in wireless high-density arrays,"
Concepts Magn Reson Part B; MR Eng, 39B(2):64-77(2011). doi: 10.1002/cmr.b.20191.
D. Bartusik, B. Tomanek, G. Fallone,
"Monitoring of 3D breast carcinoma cell culture by proton magnetic resonance imaging,"
Medicinal Chemistry Research, 19(9):1153-1161(2011). doi: 10.1007/s00044-009-9259-8.
J. Moroz, J. Turner, C. Slupsky, B.G. Fallone, A. Syme,
"Tumor Xenograft Detection through Quantitative Analysis of the Metabolic Profile of Urine in Mice,"
Phys Med Biol. 2011 Feb 7;56(3):535-56. [Featured Article].
Epub 2011 Jan 6. doi: 10.1088/0031-9155/56/3/002.
PubMed Link
T. Tadic, B.G. Fallone,
"Design and optimization of a novel bored biplanar permanent magnet assembly for hybrid MRI systems,"
IEEE Trans Magnetics, 46(12):4052-4058 (2010). doi: 10.1109/TMAG.2010.2074208
T. Tadic, B.G. Fallone,
"Three-Dimensional Non-Axisymmetric Pole Piece Shape Optimization for Biplanar Permanent Magnet MRI Systems,"
IEEE Trans Magnetics, 47(1):231-238 (2011). doi: 10.1109/TMAG.2010.2085049
P.Stavrev, C. Schinkel, N. Stavreva, B. Warkentin, M. Carlone, B.G. Fallone,
"Population TCP estimators in case of heterogeneous irradiation: A new discussion of an old problem,"
Acta Oncol. 2010 Nov;49(8):1293-303. Epub 2010 Mar 12. doi: 10.3109/02841861003649232.
PubMed Link
M. Lamey, S. Rathee, L. Johnson, M. Carlone, E. Blosser, B.G. Fallone,
"Radiofrequency noise from the modulator of a linac,"
IEEE Trans Electromagnetic Compatibility, 52(3):530-538 (Sept. 2010). doi: 10.1109/TEMC.2010.2051950
J. St-Aubin, S. Steciw, B.G. Fallone,
"Waveguide detuning caused by transverse magnetic fields on a simulated in-line 6 MV linac,"
Med Phys. 2010 Sep;37(9):4751-4. doi: 10.1118/1.3480481.
PubMed Link
J. St-Aubin, S. Steciw, D.M. Santos, B.G. Fallone,
"Effect of longitudinal magnetic fields on a simulated in-line 6 MV linac,"
Med Phys. 2010 Sep;37(9):4916-23. doi: 10.1118/1.3481513.
PubMed Link
C. Kirkby, B. Murray, S. Rathee, B.G. Fallone,
"Lung dosimetry in a linac-MR radiotherapy unit with a longitudinal magnetic field,"
Med Phys. 2010 Sep;37(9):4722-32. doi: 10.1118/1.3475942.
PubMed Link
J. St-Aubin, S. Steciw, B.G. Fallone,
"Magnetic decoupling of the linac in a low field biplanar linac-MR system,"
Med Phys. 2010 Sep;37(9):4755-61. doi: 10.1118/1.3480482.
PubMed Link
J. St-Aubin, S. Steciw, B.G. Fallone,
"Effect of transverse magnetic fields on a simulated in-line 6 MV linac,"
Physics in Medicine and Biology, 55(16):4861-4869 (Aug 21 2010). doi: 10.1088/0031-9155/55/16/015
B.G. Fallone, D. Ryan C. Rivest, T. Riauka, A. Murtha, ,
"Assessment of a commercially available automatic deformable registration,"
JACMP, 11(3):101-123 (2010 Summer). doi: 10.1120/jacmp.v11i3.3175.
PubMed Link
M. Larocque, A. Syme, J. Allalunis-Turner, B.G. Fallone,
"ADC response to radiation therapy correlates with induced changes in radiosensitivity,"
Medical Physics, 37(7):3855-3861 (July 2010). doi: 10.1118/1.3456442
A. Yahya, B.G. Fallone,
"T2 determination of the j-coupled methyl protons of lipids: in-vivo illustration with tibial bone marrow at 3 T,"
J Magn Reson Imaging. 2010 Jun;31(6):1514-21. doi: 10.1002/jmri.22195.
PubMed Link
J. Yun, J. St-Aubin, S. Rathee, B.G. Fallone,
"Brushed permanent magnet DC MLC motor operation in an external magnetic field,"
Med Phys. 2010 May;37(5):2131-4. doi: 10.1118/1.3392165.
PubMed Link
J. St-Aubin, S. Steciw, B.G. Fallone,
"An integrated 6 MV linear accelerator model from electron gun to dose in a water tank,"
Med Phys. 2010 May;37(5):2279-88. doi: 10.1118/1.3397455.
PubMed Link
K. Wachowicz, T. Stanescu, B.G. Fallone,
"Implications of tissue magnetic susceptibility-related distortion on the rotating magnet in an MR-linac design,"
Med Phys. 2010 Apr;37(4):1714-21. doi: 10.1118/1.3355856.
PubMed Link
D. Bartusik, S. Tomanek, E. Lattova, H. Perreault, B.G. Fallone,
"Ex vivo assays of CEM cells cultured and treated in the three dimensional cultures,"
Biomedicine and Pharmacotherapy, 64(6):390-395 (March 2010). doi: 10.1016/j.biopha.2010.02.004
M. Larocque, A. Syme, A. Yahya, K. Wachowicz, J. Allalunis-Turner and B.G. Fallone,
"Monitoring T2 and ADC at 9.4 T following fractionated external beam radiation therapy in a mouse model,"
Phys Med Biol. 2010 Mar 7;55(5):1381-93. Epub 2010 Feb 11. doi: 10.1088/0031-9155/55/5/008.
PubMed Link
M. Lamey, J. Yun, B. Burke, S. Rathee, B.G. Fallone,
"Radiofrequency noise from an MLC: a feasibility study of the use of MLCs for linac-MR systems,"
Phys Med Biol. 2010 Feb 21;55(4):981-94. Epub 2010 Jan 20. doi: 10.1088/0031-9155/55/4/005.
PubMed Link
M. Lamey, B. Burke, E. Blosser, S. Rathee, N. DeZanche, B.G. Fallone,
"Radiofrequency shielding for a linac-MRI system,"
Phys Med Biol. 2010 Feb 21;55(4):995-1006. [Editor’s Choice] Epub 2010 Jan 20. doi: 10.1088/0031-9155/55/4/006.
PubMed Link
B. Burke, B.G. Fallone, S. Rathee,
"Radiation induced currents in MR I- RF coils: application to linac-MR integration,"
Phys Med Biol. 2010 Feb 7; 55(3): 735–746. Epub 2010 Jan 13. doi: 10.1088/0031-9155/55/3/013.
PubMed Link
J. St-Aubin, S. Steciw, B.G. Fallone,
"The design of a simulated in-line side-coupled 6 MV linear accelerator waveguide,"
Med Phys. 2010 Feb;37(2):466-76. doi: 10.1118/1.3276778.
[selected for Virtual Journal of Biological Physics Research, Jan. 15 , 2010]
PubMed Link
D. Bartusik, B. Tomanek, E. Lattova, H. Perreault, J. Tuszynski, B.G. Fallone,
"Derivatives of thiocolchicine and its applications to CEM cells treatment using (19)F Magnetic Resonance ex vivo,"
Bioorg Chem. 2010 Feb;38(1):1-6. Epub 2009 Nov 1. doi: 10.1016/j.bioorg.2009.10.002.
PubMed Link
D. Bartusik, B. Tomanek, E. Lattova, H. Perreault, G. Fallone,
"Combined treatment of human MCF-7 breast carcinoma with antibody, cationiclipid and hyaluronic acid using ex-vivo assays,"
J Pharm Biomed Anal. 2010 Jan 5;51(1):192-201. Epub 2009 Aug 7. doi: 10.1016/j.jpba.2009.07.032.
PubMed Link
N. Pervez, C. Small, M. MacKenzie, D. Yee, M. Parliament, S. Ghosh, A. Mihai, J. Amanie, C. Field, D. Murray, G. Fallone, R. Pearcey,
"Acute toxicity in high risk prostate cancer patients treated with androgen
suppression and hypofractionated intensity modulated (IMRT),"
Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):57-64. doi: 10.1016/j.ijrobp.2009.01.048.
PubMed Link
P. Kirvan, T. Monajemi, B.G. Fallone, S. Rathee,
"Performance Characterization of a MVCT Scanner using Multi-Slice Thick, Segmented Cadmium Tungstate-Photodiode Detectors,"
Med Phys. 2010 Jan;37(1):249-57. doi: 10.1118/1.3273032.
PubMed Link
T. Stanescu, H. Jans, K .Wachowicz, B.G. Fallone,
"Investigation of a 3D system distortion correction method for MR images,"
J Appl Clin Med Phys. 2010 Winter; 11(1): 200–216. Epub 2010 Jan 28. doi: 10.1120/jacmp.v11i1.2961
PubMed Link
K. Joseph, A. Syme, C. Small, H. Warkentin, H. Quon, S. Ghosh, C. Field, N. Pervez, K. Tankel, S. Patel, N. Usmani, D. Severin, T. Nijjar, B.G. Fallone, J. Pedersen,
"A treatment planning study comparing
helical tomotherapy with IMRT for treatment of anal cancer,"
Radiother Oncol. 2010 Jan;94(1):60-6. Epub 2009 Nov 4. doi: 10.1016/j.radonc.2009.10.003.
PubMed Link
R.C. Rivest, T.A. Riauka, A.D. Murtha, B.G. Fallone,
"Dosimetric implications of two registration based patient positioning methods in prostate image guided radiation therapy (IGRT),"
Radiology and Oncology, 43(3):203-212 (2009 Sept.). doi:10.2478/v10019-009-0030-z
S. Thomas, K. Wachowicz, B.G. Fallone,
"MRI of Prostate Brachytherapy Seeds at High Field: a Phantom Study,"
Med Phys. 2009 Nov;36(11):5228-34. doi: 10.1118/1.3244036.
PubMed Link
R.C. Rivest, T. Riauka, A.D. Murtha, B.G. Fallone,
"Prostate positioning errors associated with two automatic registration based image guidance strategies,"
J Appl Clin Med Phys. 2009 Fall; 10(4): 165–176. Epub 2009 Oct 15. doi: 10.1120/jacmp.v10i4.3071.
PubMed Link
D. Bartusik, B. Tomanek, E. Lattova, H. Perreault, J. Tuszynski, B.G. Fallone,
"The efficacy of new colchicine derivatives and viability of the T-Lymphoblastoid cells in three-dimensional culture using (19)F
MRI and HPLC-UV ex vivo,"
Bioorg Chem. 2009 Dec;37(6):193-201. Epub 2009 Aug 3. doi: 10.1016/j.bioorg.2009.07.007.
PubMed Link
P. Stavrev, C. Schinkel, N. Stavreva, B.G. Fallone,
"How well are clinical gross tumor volume (DVHs) approximated by an analytical function?"
Radiol Oncol 43(2):132-135 (2009 June). doi: 10.2478/v10019-009-0016-x
A. Syme. C. Kirkby, R. Mirzayans, M. Mackenzie, C. Field, B.G. Fallone,
"Relative biological damage and electron fluence in and out of a 6 MV photon field,"
Phys Med Biol. 2009 Nov 7;54(21):6623-33. Epub 2009 Oct 14. doi: 10.1088/0031-9155/54/21/012.
PubMed Link
M.A. Mackenzie, Y. Zhao, C. Kirkby, B.G. Fallone,
"Monte Carlo evaluation of the convolution/superposition algorithm of Hi-Art tomotherapy in heterogeneous phantoms and clinical cases,"
Med Phys. 2009 May;36(5):1566-75. doi: 10.1118/1.3112364.
PubMed Link
N. Stavreva, P. Stavrev, B.G. Fallone,
"Probability dynamics of a repopulating tumor in case of fractionated external radiotherapy,"
Phys Med. 2009 Dec;25(4):181-91. Epub 2009 Apr 3. doi: 10.1016/j.ejmp.2009.01.002.
PubMed Link
L.N. Baldwin, K. Wachowicz, B.G. Fallone,
"A two step scheme for distortion rectification of magnetic resonance images,"
Med Phys. 2009 Sep;36(9):3917-26. doi: 10.1118/1.3180107.
[selected for cover of the Journal, and selected for cover
of 2011 Media Kit for Medical Physics].
PubMed Link
M. Larocque, A. Syme, A.Yahya, K. Wachowicz, J. Allalunis-Turner, B.G. Fallone,
"Temporal and dose dependence of T2 and ADC at 9.4 T in a mouse model following single fraction radiation therapy,"
Med Phys. 2009 Jul;36(7):2948-54. doi: 10.1118/1.3147258.
PubMed Link
B.G. Fallone, B. Murray, S. Rathee, T. Stanescu, S. Steciw, S. Vidakovic, E. Blosser and D. Tymofichuk,
"First MR images obtained during megavoltage photon irradiation from a prototype linac-MR system."
Med Phys. 2009 Jun;36(6):2084-8. doi: 10.1118/1.3125662.
[Awarded the Sylvia Fedoruk Prize for Medical Physics].
PubMed Link
B. Burke, M. Lamey, S. Rathee, B. Murray and B.G. Fallone,
"Radio Frequency noise from clinical linear accelerators."
Phys Med Biol. 2009 Apr 21;54(8):2483-92. Epub 2009 Apr 1. doi: 10.1088/0031-9155/54/8/015.
PubMed Link
N.Stavreva, P. Stavrev, B.G. Fallone,
"Confidence limits of the probability of success in animal experiments and clinical studies: a Bayesian approach,"
Phys Med. 2009 Mar;25(1):43-6. Epub 2008 Feb 15. doi: 10.1016/j.ejmp.2008.01.001.
PubMed Link
D. Bartusik, B. Tomanek, D. Siluk, R. Kaliszan, B.G. Fallone,
"The application of 19F magnetic resonance ex vivo imaging of three-dimensional cultured breast cancer cells to study the effect of
delta - tocopherol,"
Anal Biochem. 2009 Apr 15;387(2):315-7. Epub 2009 Jan 19. doi: 10.1016/j.ab.2009.01.010.
PubMed Link
C. Kirkby, T. Stanescu, B.G. Fallone,
"Magnetic field effects on the energy deposition spectra of MV photon radiation,"
Phys Med Biol. 2009 Jan 21;54(2):243-57. Epub 2008 Dec 16. doi: 10.1088/0031-9155/54/2/005.
PubMed Link
A. Yahya, B.G. Fallone,
"Detection of glutamate and glutamine (Glx) by turbo spectroscopic imaging,"
J Magn Reson. 2009 Feb;196(2):170-7. Epub 2008 Nov 24. doi: 10.1016/j.jmr.2008.11.007.
PubMed Link
A.A. Heikal, K. Wachowicz, Steven D. Thomas, B.G. Fallone,
"A phantom to assess the accuracy of tumor delineation using MRSI,"
Radiol Oncol 42(4):232-239 (2008 Dec.). doi:10.2478/v10019-008-0015-3
Y.Zhao, M. Mackenzie, C. Kirkby, B.G. Fallone,
"Monte Carlo evaluation of a treatment planning system for helical tomotherapy in an anthropomorphic heterogeneous phantom and for clinical treatment plans,"
Med Phys. 2008 Dec;35(12):5366-74. doi: 10.1118/1.3002316.
PubMed Link
D .Yee, R. Pearcey, G. Dundas, J. Hanson, M. Mackenzie, D. Robinson, C. Field, L.Underwood, R. Urtasun, N. Pervez, B.G. Fallone,
"Dosimetric comparison of tomotehrapy versus 4-4 field pelvic box altered fractionation
radiotherapy treatment plans for invasive squamous cell carcinoma,"
Cancer Therapy, 6, pp. 553-562 (2008).
T. Stanescu, J-S Jans, N. Pervez, B.G. Fallone,
"A study on the MRI-based radiation treatment planning of intracranial lesions,"
Phys Med Biol. 2008 Jul 7;53(13):3579-93. Epub 2008 Jun 17. doi: 10.1088/0031-9155/53/13/013.
PubMed Link
Y. Zhao, C. Kirkby, M. Mackenzie, B.G. Fallone,
"Monte Carlo calculation of helical tomotherapy dose delivery,"
Med Phys. 2008 Aug;35(8):3491-500. doi: 10.1118/1.2948409.
PubMed Link
C. Kirkby, T. Stanescu, S. Rathee, M. Carlone, B. Murray and B.G. Fallone,
"Patient dosimetry for hybrid MRI-radiotherapy systems."
Med Phys. 2008 Mar;35(3):1019-27. doi: 10.1118/1.2839104.
PubMed Link
A. Yahya, B. Maedler, B.G.Fallone,
"Exploiting the Chemical Shift Displacement Effect in the Detection of Glutamate and Glutamine (Glx) with PRESS,"
J Magn Reson. 2008 Mar;191(1):120-7. Epub 2007 Dec 25. doi: 10.1016/j.jmr.2007.12.007.
PubMed Link
E.P. Saibishkumar, M. Mackenzie, D. Severin, A. Mihai, J. Hanson, H. Daly, B.G. Fallone, M. Parliament, B. Abdulkarim,
"Skin-Sparing Radiation using Intensity-Modulated Radiotherapy After Conservative Surgery
in Early-Stage Breast Cancer: A Planning Study,"
Int J Radiat Oncol Biol Phys. 2008 Feb 1;70(2):485-91. Epub 2007 Sep 19. doi: 10.1016/j.ijrobp.2007.06.049.
PubMed Link
E.P. Saibishkumar, M. Parliament, N. Jha, M. Mackenzie, R. Scrimger, C. Field,
B.G. Fallone,
"Sparing the parotid glands and surgically transferred submandibular gland with helical tomotherapy in post-operative radiation of head and neck cancer: A planning study,"
Radiother Oncol. 2007 Oct;85(1):98-104. doi: 10.1016/j.radonc.2007.09.014.
PubMed Link
C. Schinkel, M. Carlone, B. Warkentin and B.G. Fallone,
"An analytic investigation into the effect of population heterogeneity on parameter ratio estimates."
Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1323-30. Epub 2007 Sep 20. doi: 10.1016/j.ijrobp.2007.07.2355.
PubMed Link
C. Schinkel, N. Stavreva, P. Stavrev, M. Carlone and B.G. Fallone,
"Functional form comparison between the population and the individual Poisson based TCP models."
Radiol. Oncol. 41(2):90-98 (2007 June). DOI: 10.2478/v10019-007-0016-7
A. Yahya and B.G. Fallone,
"Incorporating homonuclear polarization transfer into PRESS for proton spectral editing: Illustration with lactate and glutathione."
J Magn Reson. 2007 Sep;188(1):111-21. Epub 2007 Jun 30. doi: 10.1016/j.jmr.2007.06.009.
PubMed Link
P. Stavrev, C. Schinkel, N. Stavreva, K. Markov and B.G. Fallone,
"Analytical investigation of properties of the iso-NTCP envelope."
Radiol. Oncol. 41(1):41-47 (2007). doi: 10.2478/v10019-007-0007-8
C. Kirkby, C. Field, M. MacKenzie, A. Syme and
B.G. Fallone,
"A Monte Carlo study of the variation of electron fluence in water from a 6 MV photon beam outside of the field."
Phys Med Biol. 2007 Jun 21;52(12):3563-78. Epub 2007 May 22. doi: 10.1088/0031-9155/52/12/015.
PubMed Link
D.M. Drabik, M. Mackenzie, and B.G. Fallone,
"Quantifying appropriate PTV setup margins: analysis of patient setup fidelity and intrafraction motion using post treatment MVCT scans (TomoTherapy)."
J Radiat Oncol Biol Phys. 2007 Jul 15;68(4):1222-8. doi: 10.1016/j.ijrobp.2007.04.007.
PubMed Link
K. Breitman, S. Rathee, C. Newcomb, B. Murray, D. Robinson, C. Field, H. Warkentin, S. Connors, M. MacKenzie, P. Dunscombe and B.G. Fallone,
"Experimental Validation of the Eclipse AAA Algorithm."
J Appl Clin Med Phys. 2007 May 10;8(2):76-92. doi: 10.1120/jacmp.v8i2.2350.
PubMed Link
L.N. Baldwin, K. Wachowicz , S.D. Thomas , R. Rivest and B.G. Fallone, "Characterisation, Prediction, and Correction of Geometric Distortion in 3T MR Images,"
Med Phys. 2007 Feb;34(2):388-99. doi: 10.1118/1.2402331.
PubMed Link.