Atiyah Yahya, PhD, FCCPM, P.Eng., FCOMP
Associate Professor, Division of Medical Physics,
Department of Oncology, University of Alberta
Senior Medical Physicist, Dept. of Medical Physics CCI
B.Sc. Engineering Physics: University of Alberta,
Ph.D. Medical Sciences- Biomedical Eng., and Electrical and Computer Eng.: University of Alberta
Fellow: Canadian College of Physicists in Medicine
Member: Canadian College of Physicists in Medicine (Magnetic Resonance Imaging Physics)
Member: Canadian College of Physicists in Medicine (Diagnostic Radiology Physics)
Certification: Physics of Mammography, Canadian College of Physicists in Medicine
Fellow: Canadian Organization of Medical Physicists
Current Research Interests
My general area of research is in the field of magnetic resonance spectroscopy (MRS). I design in vivo techniques for the measurement of metabolites relevant to cancer. My work is conducted with the 3 T and 9.4 T MRI scanners housed at the Cross Cancer Institute. Recently, I have been working on improving proton MRS quantification of lipids. In addition to technical development, I am interested in applying MRS to monitor changes in metabolite levels in response to treatment.
Selected Publications
E. Saive, L. Fairgrieve-Park, A. Yahya,
"Estimating relative diglyceride to triglyceride content with localized MRS at 3 T",
NMR in Biomedicine 35:e4723, 10 pages (2022)
C.J. Fallone, A.G. Tessier, A. Yahya,
"Fat unsaturation measures in tibial, subcutaneous and breast adipose tissue using short and long TE MRS at 3 T.",
Magnetic Resonance Imaging 86: 61-69 (2022)
C.J. Fallone, A.G. Tessier, Catherine J. Field, A. Yahya,
"Resolving the omega-3 methyl resonance with long echo time magnetic resonance spectroscopy in mouse adipose tissue at 9.4 T",
NMR in Biomedicine 34:e4455, 11 pages (2021)
B.J. Dobberthien, A.G. Tessier, A.E. Stanislaus, M.B. Sawyer, B.G. Fallone, A. Yahya, "PRESS timings for resolving 13C4-glutamate 1H signal at 9.4 T: Demonstration in rat with uniformly labelled 13C-glucose",
NMR in Biomedicine 32:e4180, 13 pages (2019)
B.J. Dobberthien, V. Volotovskyy, A.G. Tessier, A. Yahya,
"Magnetic resonance spectroscopy of rat kidney in vivo at 9.4 T",
Biomedical Physics and Engineering Express, 5: 045035 (2019)
C.J. Fallone, A. Yahya,
"Effect of triglyceride glycerol CH signal on olefinic resonance quantification with proton magnetic resonance spectroscopy at 3 T",
Biomedical Physics and Engineering Express, 5: 027004 (2019)
L. Fairgrieve-Park, C.J. Fallone, A. Yahya,
"Long TE PRESS and STEAM for measuring the triglyceride glycerol CH2 protons at 3 T",
NMR in Biomedicine 32:e4021, 8 pages (2019).
C.J. Fallone, R.T. McKay, A. Yahya,
"Long TE STEAM and PRESS for Estimating Fat Olefinic/Methyl Ratios and Relative ω-3 Fat Content at 3T",
Journal of Magnetic Resonance Imaging 48:169-177 (2018) .
B.J. Dobberthien, A.G. Tessier, A. Yahya,
"Improved resolution of glutamate, glutamine and γ-aminobutyric acid with optimized point-resolved spectroscopy sequence timings for their simultaneous quantification
at 9.4 T",
NMR in Biomedicine 31:e3851, 12 pages (2018) .
M.E. Fisher, B.J. Dobberthien, A.G. Tessier, A. Yahya,
"Characterization of the Response of Taurine Protons to PRESS at 9.4 T for Resolving Choline and Determining Taurine T2",
NMR in Biomedicine 29:1427-1435 (2016).
L.J. Vos, M. Janoski, K. Wachowicz, A. Yahya, O. Boychak, J. Amanie, N. Pervez, M.B. Parliament, E. Pituskin, B.G. Fallone, N. Usmani,
"Role of serial multiparametric magnetic resonance imaging in prostate
cancer active surveillance",
World Journal of Radiology 8:410-418 (2016).
B.J. Dobberthien, A.G. Tessier, B.G. Fallone, A. Yahya,
"Optimized PRESS sequence timings for measuring glycine at 9.4 T: demonstration in vivo in rat brain",
Biomedical Physics and Engineering Express 2:027003 (2016).
D.Y. Breitkreutz, B.G. Fallone, A. Yahya,
"Effect of J coupling on 1.3-ppm lipid methylene signal acquired with localised proton MRS at 3 T",
NMR in Biomedicine 28:1324-1331 (2015).
Q.M. Barber, A. Yahya,
"Aspects of spinal bone marrow fat to water quantification with magnetic resonance spectroscopy at 3 T",
Biomedical Physics and Engineering Express 1:047001 (2015).
A. Bingölbali, B.G. Fallone, A. Yahya,
"Comparison of Long Echo Time STEAM and PRESS Proton MR Spectroscopy of Lipid Olefinic Protons at 3 T",
Journal of Magnetic Resonance Imaging 41:481-486 (2015).
A. Tessier, A. Yahya, M. Larocque, B.G. Fallone, A. Syme,
"Longitudinal evaluation of the metabolic response of a tumor xenograft model to single fraction radiation therapy using magnetic resonance spectroscopy".
Physics in Medicine and Biology 59:5061-5072 (2014).
A. Yahya, N. De Zanche, P.S. Allen,
"A Dual-Tuned Transceive Resonator for 13C {1H} Magnetic Resonance Spectroscopy: Two Open Coils in One",
NMR in Biomedicine 26:533-541 (2013).
A. Troitskaia, B.G. Fallone, A. Yahya,
"Long Echo Time Proton Magnetic Resonance Spectroscopy for Estimating Relative Measures of Lipid Unsaturation at 3 T.."
Journal of Magnetic Resonance Imaging 37:944-949 (2013).
A. Yahya, A.G. Tessier, B.G. Fallone,
"Effect of J-Coupling on Lipid Composition Determination with Localized Proton Magnetic Resonance Spectroscopy at 9.4 T.,"
Journal of Magnetic Resonance Imaging 34:1388-1396 (2011).
A. Yahya, B.G. Fallone,
"T
2 Determination of the J-Coupled Methyl Protons of Lipids: In-Vivo Illustration with Tibial Bone Marrow at 3 T.,"
Journal of Magnetic Resonance Imaging 31: 1514-1521 (2010).
M.P. Larocque, A Syme, A Yahya, K Wachowicz, J Allalunis-Turner and BG Fallone,
"Monitoring T2 and ADC at 9.4 T following fractionated external beam radiation therapy in a mouse model,"
Phys Med Biol, 55(5), pp. 1381-1391 (2010).
M.P. Larocque, A. Syme, A.Yahya, K. Wachowicz, J. Allalunis-Turner, B.G. Fallone,
"Temporal and dose dependence of T2 and ADC at 9.4 T in a mouse model following single fraction radiation therapy,"
Medical Physics, 36(7), pp. 2948-2954 (2009).
A. Yahya,
"Metabolite Detection by Proton Magnetic Resonance Spectroscopy using PRESS,"
Progress in Nuclear Magnetic Resonance Spectroscopy 55: 183-198 (2009).
A. Yahya, B.G. Fallone,
"Detection of Glutamate and Glutamine (Glx) by Turbo Spectroscopic Imaging."
Journal of Magnetic Resonance. 196: 170-177
(2009).
A. Yahya, B. Mädler, B.G. Fallone,
"Exploiting the Chemical Shift Displacement Effect in the Detection of Glutamate and Glutamine (Glx) with PRESS."
Journal of Magnetic Resonance. 191: 120-127
(2008).
A. Yahya, B.G. Fallone,
"Incorporating Homonuclear Polarization Transfer into PRESS for Proton Spectral Editing: Illustration with Lactate and Glutathione."
Journal of Magnetic Resonance. 188: 111-121
(2007).
A. Yahya, P.S. Allen,
"The Effect of Strong Homonuclear Proton Coupling on Localized 13C Detection Using PRESS."
Magnetic Resonance in Medicine. 54: 1340-1350
(2005) .
N. De Zanche, A. Yahya, F.E. Vermeulen, P.S. Allen,
"An Analytical Approach to Non-circular Section Birdcage Coil Design: Verification with a Cassinian. Oval Coil."
Magnetic Resonance in Medicine. 53: 201-211
(2005).